He was born on the Peloponnese, and became Archbishop of Smyrna in 1785. He served at a time when revolutionary feeling and activity was increasing among the Greek people, and witnessed the cruel retribution that the Ottoman Turks visited on any evidence of rebellion among their subject people.

Once in Smyrna, seeing that an action he had taken was causing discord in his dioceses, he came down from the hierarchical throne during a service, prostrated himself before the faithful and asked their forgiveness.

He was elected Patriarch of Constantinople in 1797. Under the Turkokratia, the Patriarch was not only the head of the Greek churches but the secular ruler of the Greek people, bound by oath to respect the authority of the Sultan. This, combined with Gregory’s personal experience of the treatment of Greek rebels, made him a staunch opponent of revolutionary activity among his people. Still, when revolutionaries on the Peloponnese declared Greek independence from Turkey on March 25, 1821, Turkish retribution was harsh: On Pascha, April 10, after serving the Paschal Liturgy, the aged Patriarch was arrested by the Turkish authorities. He was tortured in an effort to have him reveal the names of those heading the revolution, then was offered his freedom if he would convert to Islam. Gregory answered, ‘You ask in vain: the Patriarch of Christians dies a Christian.’ He (along with other clergy and hierarchs) was hanged as a traitor on the gate of the patriarchal compound. An eyewitness, a British clergyman visiting Constantinople, wrote: ‘His body, attenuated by abstinence and emaciated by age, had not sufficient weight to cause immediate death. He continued for a long time in pain which no friendly hand dared abridge, and the darkness of night came on before his final convulsions were over.’ His body was left hanging for three days, then sold by the Turkish authorities to a Jewish mob, who mutilated the body, then weighted it about the neck with a stone and threw it into the sea. Despite this, the body was found floating at sea by a Greek merchant ship captain. When the body was identified as that of the martyred Patriarch, it was secretly taken to Odessa, where Orthodox church leaders took it under their care. Tsar Alexander I ordered a state funeral for the holy hierarch, which was celebrated on June 17 1821 in Odessa.

In 1871 the relics were returned to Greece by Tsar Alexander III. They were incorrupt, though fifty years had passed since his death. Saint Gregory was officially glorified in 1921. His relics may be venerated at the Metropolitan Cathedral in Athens.

Prologue from Ochrid